How does 6-MP work?

6-Mercaptopurine (6-MP) is an immunosuppressive medication that works by inhibiting purine metabolism, which is essential for the synthesis of DNA and RNA in rapidly dividing cells, such as those in the immune system. It is converted to active metabolites that interfere with the proliferation of lymphocytes, thereby reducing the immune response. This mechanism makes 6-MP effective in treating conditions like leukemia and autoimmune diseases. Additionally, it can lead to cell death in malignant cells due to its role as a purine analog.