What is the size of endotoxin?

Endotoxins, which are components of the outer membrane of Gram-negative bacteria, typically range in size from about 5 to 10 kilodaltons (kDa). These complex molecules consist of a lipid portion (lipid A) and a polysaccharide portion, with the lipid A being the primary toxic component. Due to their relatively small size, endotoxins can elicit strong immune responses and are a significant concern in medical settings, especially regarding contamination in pharmaceuticals and medical devices.