If you take methadone will you have a bad interaction if you take Tylenol with codeine?

Taking methadone with Tylenol (acetaminophen) and codeine can increase the risk of respiratory depression, sedation, and other side effects due to the combined effects of opioids. Both medications are central nervous system depressants, so using them together should be done with caution and under medical supervision. Always consult your healthcare provider before combining these medications to ensure safety and proper dosage.