Polymixin b is better than polymixin e?

Polymyxin B and Polymyxin E (also known as Colistin) are both antibiotics used to treat infections caused by multidrug-resistant Gram-negative bacteria. Polymyxin B is often preferred in clinical settings due to its more favorable pharmacokinetic profile, including better tissue penetration and lower nephrotoxicity compared to Colistin. Additionally, Polymyxin B has a more established safety profile and is less likely to cause neurotoxicity. Therefore, while both are effective, Polymyxin B is often considered the better option in certain therapeutic contexts.