Can you get brain damage from a sharpie?

While using a Sharpie in well-ventilated areas is generally safe, inhaling the fumes from the ink or using it excessively in enclosed spaces can lead to headaches, dizziness, or respiratory issues. Prolonged exposure to solvents found in some permanent markers can potentially cause neurological effects, but this typically requires significant and repeated exposure. For casual use, brain damage from a Sharpie is unlikely. Always use art supplies as intended and in appropriate environments to minimize any risks.