For the meat to be properly cooked the internal temperature should be a minimum of 165°, preferably 170°, for 5 minutes. Set your thermometer alarm for 165°, and when it goes off, remove the meat loaf from the 325° oven. Cover and let rest for 10 minutes. The temperature will raise another 5° while resting. Also, the juices will set, and you won't have a dry meat loaf!
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