How quickly is fosamax absorbed?

Fosamax (alendronate) is rapidly absorbed after oral administration, with peak plasma concentrations typically occurring within 1 to 2 hours. However, its bioavailability is low, approximately 0.7% to 1% when taken orally, mainly due to poor absorption in the gastrointestinal tract. To enhance absorption, it is recommended to take Fosamax on an empty stomach with a full glass of water, and to avoid eating or drinking anything else for at least 30 minutes afterward.