Why is lactate dehydrogenase elevated in viral hepatitis?

Lactate dehydrogenase (LDH) is elevated in viral hepatitis due to liver cell damage and necrosis caused by the viral infection. As hepatocytes are destroyed, LDH, which is normally found in these cells, leaks into the bloodstream, leading to increased serum levels. Additionally, the inflammatory response during viral hepatitis can further contribute to cellular damage and the release of LDH. Therefore, elevated LDH levels can serve as a marker of liver injury in this condition.