How many more people preferred 41 percent than 22 percent?

Depends on what you are talking about.

If it is a good thing, 100% of the people will want 41% rather than 22%.

• I'll give you x% of the money.
• You can have x % of the cookies.

If it is a bad thing, 100% of the people will want 22% rather than 41%.

• There is an x% chance of rain during the picnic.
• There is a x% chance you have cancer.