Why does excessive alcohol intake lead to hypoglycemia and lactic acidosis?

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1079148

2026-02-26 05:25

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Excessive alcohol intake can lead to hypoglycemia because alcohol metabolism inhibits gluconeogenesis in the liver, reducing the production of glucose. Additionally, alcohol increases the production of NADH during its metabolism, which shifts the balance of metabolic pathways and promotes lactic acid fermentation, leading to lactic acidosis. The combination of impaired glucose production and increased lactic acid in the bloodstream can result in both hypoglycemia and lactic acidosis.

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