When is TPN contraindicated?

Total parenteral nutrition (TPN) is contraindicated in patients with functional gastrointestinal tracts, as they should receive enteral nutrition instead. It is also not recommended for individuals with severe metabolic disorders, such as certain inborn errors of metabolism, or in cases of acute pancreatitis where the gastrointestinal tract can be used. Additionally, TPN should be avoided in patients with severe fluid overload or those with a high risk of complications from catheter placement.