Is ALS hereditary

Amyotrophic lateral sclerosis (ALS) can be hereditary in some cases, known as familial ALS, which accounts for about 5-10% of all cases. The majority of ALS cases are sporadic, meaning they occur without a clear genetic link. Certain genetic mutations, such as those in the C9orf72, SOD1, and TARDBP genes, have been associated with familial ALS. However, even in sporadic cases, genetic factors may still play a role alongside environmental influences.