Why do anti-depressants make less urination?

Antidepressants can affect urination due to their impact on neurotransmitters that regulate bladder function. Many antidepressants, particularly those with anticholinergic properties, can inhibit the activity of acetylcholine, a neurotransmitter involved in bladder contraction. This inhibition may lead to reduced urgency and frequency of urination. Additionally, some antidepressants can also influence fluid balance and kidney function, further contributing to decreased urination.