As you probably know, Harley doesn't make tires and never have. But any Harley with factory wire wheels (spoke type) uses inner tubes, and any Harley with factory cast aluminum wheels can use tubeless tires.
But not all tires can be used without a tube, it depends on the type and manufacturer. It will say on the tire's sidewall if it can be run tubeless.
Harley first started using cast aluminum tubeless-type wheels in the late Seventies.
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