Can you take nexium and prevacid together?

No... you should avoid anti-inflammatory drugs while taking Celebrex. Excedrin contains aspirin which might lead to suppress the "gastric protection" from celebrex.

This is not a major interaction, but if you're older or at risk of gastric events, you should avoid those 2 drugs together.

You may try "Tylenol Ultra relief" which contain acetaminophen and caffeine, without aspirin.