What causes low alpha 1 globulin in bloods?

Low alpha-1 globulin levels in the blood can be caused by several factors, including genetic disorders such as Alpha-1 Antitrypsin Deficiency, liver disease, or malnutrition. Conditions that lead to increased protein loss, such as nephrotic syndrome or chronic inflammation, may also contribute. Additionally, certain medications and systemic diseases can affect protein synthesis and lead to reduced levels of alpha-1 globulins. Regular monitoring and diagnostic evaluations are important for identifying the underlying causes.