How long does aprazolam stay in your system before you can drink alcohol?

Alprazolam (Xanax) half life* is: Immediate release: 11.2 hours; Extended release: 10.7-15.8 hours. Your answer depends on the dosage you are taking. We have no way of knowing that, but we would strongly suggest that you not drink until most of it is out of your system.

You should know that alprazolam withdrawal can take several days to a couple of week, and there is danger of seizures and blood pressure spikes that can cause strokes if it is withdrawn quickly without medical support. The same is true of alcohol.

*Half life is the time it takes your body to metabolize 1/2 of the drug that is in your system. In the case of Xanax, the metabolites are also active drugs, so it takes much longer for your body to reach a safe level.