What does it mean when your female Betta has a hole in her body?

A hole in a female Betta's body could indicate a serious health issue, such as an infection or disease, such as hole-in-the-head disease, which is often caused by poor water quality or stress. It may also result from physical injury or aggressive behavior from tank mates. It's essential to assess the water conditions, provide appropriate treatment, and isolate the fish if necessary. Consulting a veterinarian or an aquarium specialist can help determine the exact cause and the best course of action.