malaria is caused by the microscopic single -celled protozoan called Plasmodium , and is the deadliest organism on the planet. When a person with active malaria is bitten by the Anopheles mosquito, the mosquito injests the Plasmodium larvae with the blood meal. The larvae travel to the midgut of the mosquito, where they change form. When the mosquito bites UNinfected person, the plasmodium is injected into their bloodstream through the mosquito's saliva. The larvae are in the person's bloodstream , and transform again. Next they invade the blood cells, where they multiply over and over, bursting the blood cells and spreading even more larvae into the blood stream. The infection causes high fevers, and severe anemia, possibly leading to death. Another mosquito bites this person and spreads it to yet a third person.
( i think I left out a side-trip into the human liver somewhere, but you get the idea!)
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