Are Bow Wow and Lil Mama bother and sister?

No, Bow Wow and Lil Mama are not brother and sister. They are both artists in the hip-hop industry, but they are not related. Bow Wow, whose real name is Shad Moss, is a rapper and actor, while Lil Mama, whose real name is Niatia Jessica Kirkland, is a rapper and singer. They have collaborated in the past but share no familial ties.