Do you need prescription to buy EPI pen?

What is the reason you ask? For allergic reactions, I seriously doubt it- it can have serious effects on the body and isn't easily attainable because of them. You can't keep it on hand "just in case" in a first aid kit unless you've had someone who has previously had a reaction and had it prescribed for them. But there are forms of epinephrine in some nasal sprays for opening up the vessels in the nasal cavities.