Method of attack do toxin use?

There are as many ways that toxins work as there are toxins.
For example botulinum toxin (made by a bacteria) is the most powerful neurotoxin known to date. Only one single molecule of it is needed to stop one neuron (nerve cell) working. 1 gram of botulinum toxin would be enough to kill 14,000 people (if ingested), 1.25 million people if inhaled, or a staggering 8.3 million people if injected.

Air pollutant (toxins) is in also cigarettes. Inhaled tobacco products contain a number of highly toxic ingredients that can negatively effect your body and can produce cancer.

Superantigens produced by the strains of Staphylococcus aureus and Streptococcus pyogenes cause Toxic shock syndrome. That acts upon the cardiovascular system causing total body shut down.

Well known examples of toxins include pit vipers, such as rattlesnakes, that possess hemotoxins that target and destroy red blood cells and are transmitted through the bloodstream; the brown recluse or "fiddle back" spider that uses necrotoxins that cause death in the cells they encounter and destroy all types of tissues; and the black widow spider, most scorpions, the box jellyfish, elapid snakes, and the cone snail that use neurotoxins that primarily affect the nervous system of animals.