Who has most famous painting depicts sin and redemption?

The most famous painting that depicts sin and redemption is "The Last Judgment," created by Michelangelo. This monumental fresco, located on the altar wall of the Sistine Chapel in Vatican City, illustrates the final judgment of souls by Christ, showcasing the themes of salvation and damnation. Through its dramatic figures and intense expressions, the artwork powerfully conveys the consequences of sin and the hope of redemption.