When does the level of estrogen fall?

Estrogen levels typically fall during menopause, which usually occurs between the ages of 45 and 55. This decline is due to the ovaries producing less estrogen as they age and eventually stop releasing eggs. Additionally, estrogen levels can fluctuate during the menstrual cycle, reaching their lowest point just before menstruation begins. Other factors, such as certain health conditions or hormonal treatments, can also lead to decreased estrogen levels.