One of these Words (affect) is a verb -- an action Word. The other (effect) is a noun. You can remember the one that is a verb because "affect" begins with an "a," and it shows action: The flu affects each person differently. "Your tardiness will affect your grade," said the teacher. (To affect means to impact or influence.)
As for the noun (which begins with the letter "e"), use it like this: I don't know if this will have a good effect, but I think we should try it. The Word "effect" often refers to a result, and it often has an adjective right next to it-- a good effect, a bad effect, a positive effect, a negative effect, etc.
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