If you operated a trucking service between San Francisco California and Portland Oregon could you subject to regulation by either or both of the states and the federal government?

Yes, if you operated a trucking service between San Francisco, California, and Portland, Oregon, you would be subject to regulation by both states and the federal government. State regulations would govern aspects such as permits, safety standards, and weight limits, while federal regulations, including those from the Federal Motor Carrier Safety Administration (FMCSA), would apply to interstate commerce. Compliance with both levels of regulation is necessary to operate legally and safely across state lines.