How do you remove a toad's brain?

To remove a toad's brain you have to use a process called pithing. You bend the toad or frog right behind the head. Take a large needle and slide it up into the brain. Twist it around and move it back and forth. That will destroy the brain. Turn the pith needle around and push it down through the spinal cord. Move it around a little bit. Now the spinal cord is destroyed.