Amphetamines carry a risk of physical dependence or addiction?

Yes, amphetamines can lead to physical dependence and addiction due to their stimulating effects on the central nervous system. Prolonged use can alter brain chemistry, resulting in tolerance, where higher doses are needed to achieve the same effects. This can lead to withdrawal symptoms when the drug is not taken, reinforcing the cycle of dependence. It's important to use amphetamines only as prescribed by a healthcare professional to minimize these risks.