Can you take Zyrtec Lyrica oxycodone and amitriptyline together?

Taking Zyrtec (an antihistamine), Lyrica (pregabalin), oxycodone (an opioid pain reliever), and amitriptyline (a tricyclic antidepressant) together can increase the risk of side effects such as sedation, dizziness, and respiratory depression. It's crucial to consult a healthcare professional before combining these medications, as they can interact in ways that may be harmful. Your doctor can provide personalized advice based on your health history and specific circumstances.