How can I safely and efficiently go about cashing a 100,000 check?

To safely and efficiently cash a 100,000 check, you should go to the bank where the check is drawn from and deposit it into your account. Make sure to bring proper identification and be prepared for the bank to place a hold on the funds to verify the check's authenticity. It's also a good idea to notify the bank in advance about the large deposit to avoid any potential issues.