What is a sponge sponge domain?

A sponge domain is a type of protein domain characterized by its ability to bind and regulate various biomolecules, often involved in cellular signaling or structural functions. These domains are typically rich in proline, glycine, and other flexible residues, giving them a "sponge-like" quality that allows them to accommodate different partners. Sponge domains play a crucial role in cellular processes by modulating interactions with other proteins, RNAs, or lipids, thereby influencing various biological pathways.