It's generally not advisable to mix Alka-Seltzer (an antacid) with ecstasy (MDMA) due to the potential for increased strain on your body and the risk of dehydration. Alka-Seltzer can cause stomach discomfort, and using it while on ecstasy could exacerbate side effects like nausea. If you're considering taking any medications while using recreational drugs, it's best to consult a healthcare professional first.
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