Diffuse atrophy of the thyroid gland can lead to hypothyroidism, a condition characterized by insufficient production of thyroid hormones. This can result in symptoms such as fatigue, weight gain, cold intolerance, and depression. Additionally, it may cause elevated levels of thyroid-stimulating hormone (TSH) as the pituitary gland attempts to stimulate the underactive thyroid. Long-term atrophy can also contribute to goiter development or other thyroid-related disorders.
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