What are limitations of blood typing?

Blood typing has several limitations, including the potential for misinterpretation due to mixed or weak reactions that can lead to incorrect typing results. Additionally, it does not account for the presence of rare blood group antigens, which can complicate transfusions and increase the risk of hemolytic reactions. Blood typing also cannot identify all possible antibodies present in a patient's serum, which is crucial for safe transfusion practices. Finally, environmental factors and sample handling can affect the accuracy of results.