Though the answer is mostly determined by game strategy and style, these are some of the best synchro monsters around:
Brionac, dragon of the ice barrier
(limited due to its mutli-trigger effect and super easy summon. Offers solid 2300ATK/1400DEF)
Stardust Dragon
(first and longest lasting staple card for synchros due to its ability to negate card effects that destroy cards. Offers decent 2500ATK/2000DEF)
Goyo Guardian
(banned due to its super easy summoning condition, amazing effect special summon any monster it destroys by battle, and massive 2800ATL/2000DEF for a level 6!)
Mist Wurm
(awesome potential to return up to 3 cards your opponent controls back to their hand. Offers decent, but low 2500ATK/1500DEF)
Dark Strike Fighter
(banned due to a powerful 2600ATK/1800DEF, super easy to get out, and offers a game changing and game ending effect to tribute monsters and burn your opponent!)
Flamvell Uruquizas
(Offers good 2100ATK, has piercing damage, and gets stronger every time it inflicts battle damage to your opponent)
Red Dragon Archfiend
(though risky in your part, wipes out your opponent's defense and offers a massive 3000ATK)
Ally Of Justice Catastor
(offers solid 2200ATK, super easy to get out, and destroys any non-dark monster it battles)
Trishula, Dragon Of The Ice Barrier
(Easy to get out, powerful 2700ATK/2000DEF, and removes from play any card in their graveyard, hand, AND field)
Ally Of Justice Decisive Armor
(Offers massive 3300ATK/3300DEF, easy to get out, and offers three good-awesome abilities to wipe out your opponent)
Scrap Dragon
(Easy to get out, Powerful 2800ATK/2000DEF, and can destroy any one of your opponent's cards at the SMART choice of your own)
Black Rose Dragon
(Easy to get out, Offers solid 2400ATK/1700DEF, and wipes out the entire field)
Colossal Fighter
(Easy to get out, Massive 2800ATK, can revive itself when destroyed by battle, and powers itself up)
Formula Synchron
(Easy to get out, offers draw power when summoned, and IS A TUNER ITSELF!)
Magical Android
(Offers powerful 2400ATK, easy to get out, and heals you at the end of every turn)
Red Nova Dragon
(Powers up from every tuner in your graveyard, not TOO hard to get out, can't be destroyed by card effect, and can negate your opponent's attacks)
Shooting Star Dragon
(Solid 3300ATK/2500DEFand offers 3 nice abilities that can be activated EACH once per turn)
Majestic Red Dragon
Level: 10, Attribute: Dark, Type: Synchro Effect Monster, SubType: Dragon
Majestic Star Dragon
Level: 10, Attribute: Wind, Type: Synchro Effect Monster, SubType: Dragon
Nitro Warrior
Level: 7, Attribute: Fire, Type: Synchro Effect Monster, SubType: Warrior
Junk Warrior
Level: 5, Attribute: Dark, Type: Synchro Effect Monster, SubType: Warrior
Junk Destroyer
Level: 8, Attribute: Earth, Type: Synchro Effect Monster, SubType: Warrior
Road Warrior
Level: 8, Attribute: Light, Type: Synchro Effect Monster, SubType: Warrior
Turbo Warrior
[Warrior/Synchro/Effect] Turbo Synchron + 1 or more non-Tuner monsters. When this card attacks a Level 6 or higher Synchro Monster, halve that monster's ATK until the end of the Damage Step. This card cannot be targeted by the effects of Level 6 or lower monsters.
Ancient Fairy Dragon
Level: 7, Attribute: Light, Type: Synchro Effect Monster, SubType: Dragon
Power Tool Dragon
Level: 7, Attribute: Earth, Type: Synchro Effect Monster, SubType: Machine
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