When is the best time to give anti tetanus after a puncture?

The best time to administer anti-tetanus prophylaxis after a puncture wound is as soon as possible, ideally within 24 hours. If the individual's vaccination status is uncertain or if it's been more than 10 years since the last booster for a dirty or high-risk wound, a booster dose of tetanus toxoid should be given. For clean and minor wounds, the booster may be given if it has been more than 10 years since the last dose. Always consult a healthcare professional for specific recommendations based on individual circumstances.