Yes, you can generally take Zyrtec (an antihistamine) and Alka-Seltzer Plus Severe Sinus (which often contains a combination of decongestants and pain relievers) together. However, it's important to check the specific ingredients in the Alka-Seltzer product to ensure there are no potential interactions or overlapping ingredients. Always consult with a healthcare professional or pharmacist before combining medications to ensure safety, especially if you have any underlying health conditions.
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