To replace the transponder coil on a 2001 Mercedes SLK320, first disconnect the vehicle's battery to ensure safety. Remove the ignition switch assembly, which may involve taking off the steering column cover and disconnecting any wiring harnesses. Carefully replace the old transponder coil with the new one, ensuring it's properly aligned, then reassemble the ignition switch and reconnect the battery. Finally, test the new coil by attempting to start the vehicle with the key.
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