What effect does the setting have on the plot at the beginning of the story the monkeys paw?

The setting of a remote, isolated house in a deserted area contributes to the sense of suspense and mystery in "The Monkey's Paw." It sets the stage for the introduction of the magical talisman and the consequences that follow, creating a sense of foreboding in the plot. The eerie and ominous setting foreshadows the darker events that unfold as the story progresses.