Yes, 22-inch rims can fit on a 2001 Pontiac Grand Prix, but several factors must be considered. You will need to ensure that the overall diameter of the new wheels and tires does not exceed the vehicle’s clearance and that the bolt pattern and offset are compatible. Additionally, modifications to the suspension or fenders may be necessary to prevent rubbing. It's advisable to consult with a professional to ensure proper fitment and safety.
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