Yes, in the PlayStation 2 version of Resident Evil 4, you can unlock all weapons by completing the game once and then starting a new game with the "New Game Plus" option. Additionally, you can enter a cheat code during gameplay: pause the game and press L1, L1, R1, R1, L1, L1, R1, R1 to unlock all weapons. However, using cheats may affect your gameplay experience, so it's best to use them wisely.
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