Is Zac Efron related to Nora Ephron?

No, Zac Efron and Nora Ephron are not related. Although pronounced the same, they spell their last names differently.

Zac Ephron was born October 18, 1987 in San Luis Obispo, California. His parents names are Davis and Starla. He has a brother named Dylan. There is apparently no relation between him and Nora.