The first thing that you need to know is if it is a true allergy or simply a strong manifestation of the common opioid side effects. If you do have a true allergy to codeine, you could be allergic to some or all of the semi-synthetic preparations or you could be fine with them. The semi-synthetic codeines include hydrocodone, oxycodone, and any other -codone named medications.
You should also be aware that drug Allergies can begin at any time. While you may have taken hydrocodone without incident for years, you may find yourself having a life-threatening reaction to it at any time. Once you have a reaction to codeine or a synthetic preparation, you are at an increased risk of reacting to the other preparations. It would be wise to keep epinepherine and diphenhydramine available if you are going to test the waters with any others.
If you find yourself allergic to codeine or the semi-synthetic preparations, you may want to talk to your doctor about prescribing a medication from the morphine group as allergies to codeine and morphine are generally unrelated.
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