It depends on why you are framing it, what material the serigraph is on (cloth or paper, or something else...), and how long you want it to last. The main reason for glass in framing is usually protection from people... touching an artwork can sometimes hurt it over a long period of time. If the concern is only to display the silkscreen print, then personal preference rules. See this page for other matting and framing discussion: http://www.princetonaudubon.com/HTML%20Pages/matting_and_framing.htm Most paper products should be framed with glass, this is mainly for protection from airborn pollutants. Most framers will advise that you space the glass with either a mat or a spacer.
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