Wellbutrin (bupropion) has a half-life of approximately 21 hours, meaning it takes about that long for half of the drug to be eliminated from your system. Generally, it can take about 5 to 7 half-lives for a drug to be cleared from your system, which would suggest that 75 mg of Wellbutrin may remain in your system for around 4 to 6 days. However, this can vary based on individual factors such as metabolism, age, and overall health. Always consult a healthcare provider for personalized information.
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