What would happen to red blood cells if the haem group were removed from hemoglobin?

If the heme group were removed from hemoglobin, red blood cells would lose their ability to bind and transport oxygen effectively. Hemoglobin's primary function is to carry oxygen from the lungs to tissues, and the heme group's iron atom is crucial for this process. Without it, red blood cells would struggle to meet the oxygen demands of the body, leading to symptoms of hypoxia and reduced overall cellular function. Additionally, the red blood cells would not be able to participate in the transport of carbon dioxide back to the lungs for exhalation.