Can you take amoxicillin and calpol at the same time?

can my 2 year daughter take amoxicillian with calpol at the same time

Yes, absolutely. They are totally different drugs. Amoxicillin is a penicillin/antibiotic, and Calpol is the brand name for Paracetamol, which is an analgesic (pain relief) and anti-pyretic (reduces fever). It is advisable in fact to use both, particularly in a child of that age, who is susceptible to febrile convulsions if a fever is left untreated (assuming that is what you are using the Calpol for).