To change the fuel filters on a 2008 Ford F-350 diesel, first ensure the engine is off and cool. Locate the primary fuel filter, which is typically on the driver's side frame rail, and the secondary filter, found on the engine. Use a filter wrench to remove the old filters, and make sure to clean the mounting surfaces. Install the new filters, ensuring they are tightly secured, and prime the system by turning the ignition to the "on" position for a few seconds before starting the engine.
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