The Word "choir" can be either one or two syllables, because the O and the I (while not a vowel pair as in "oy") can be pronounced together as a long I.
The one-syllable version is the same as "quire" with a KW sound from the QU.
This rhymes with "lyre."
The two-syllable version is (kwy-ur) with the R having a schwa sound as in "liar."
* Lyre and liar are homophones in US English.
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