Will you lose your cdl license for a dwi in Texas?

Yes. It'll be suspended. Once you have your licence reinstated, you'll have a CDL, once again. Of course, it'll do you no good. For the three years following your DUI conviction, you can forget about finding employment as a CDL driver - no company will touch you. For the next two years after that, your odds look a little better - instead of impossible, it'll only be next to impossible. For the next five years following, you're still going to be pretty "undesirable" to a prospective employer, but they might hire you if they're hard up for drivers.